38 overweight or obese people participated in a 12-week clinical research in which they were given either a low-AGE or high-AGE diet.
According to a new first-of-its-kind clinical experiment, foods high in advanced glycation end products (AGEs), such as cakes, chips, cookies, crackers, fried meals, mayonnaise, margarine, and ultra-processed foods, are largely to blame for India’s status as the global center of the diabetes epidemic. These substances have the potential to cause inflammation and other diabetes-related health problems.
According to a study, India’s diabetes epidemic is “first-of-its-kind” and is caused by fried, baked, and highly processed foods.
38 overweight or obese people participated in a 12-week clinical research in which they were given either a low-AGE or high-AGE diet.
According to a new first-of-its-kind clinical experiment, foods high in advanced glycation end products (AGEs), such as cakes, chips, cookies, crackers, fried meals, mayonnaise, margarine, and ultra-processed foods, are largely to blame for India’s status as the global center of the diabetes epidemic. These substances have the potential to cause inflammation and other diabetes-related health problems.
According to the researchers’ paper, “this dietary change could help reduce the impact of obesity-related type 2 diabetes.”
One of the authors, Dr. V. Mohan, chairman of the Madras Diabetes Research Foundation (MDRF), stressed to The Print that India’s strategy to fight diabetes depends on knowing which foods are high in AGEs and how they occur.
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Results of clinical trials
The prevalence of diabetes in India hit a startling 11.4 percent in 2021, according to a study by the Indian Council of Medical Research (ICMR) and MDRF that was published in “The Lancet Diabetes & Endocrinology” in June 2023. This indicates that approximately 101 million Indians received a diabetes diagnosis in that particular year.
Consuming highly processed meals that are heavy in fat, sugar, salt, and AGEs has been linked to an increased risk of chronic diseases, according to previous study from Western countries.
A recent study emphasizes how dietary decisions affect diabetes and obesity in India. Researchers discovered that a sedentary lifestyle and the fast nutrition transition in developing nations have boosted the consumption of animal products, lipids, and refined carbohydrates, increasing the risk of chronic illnesses.
Notably, little is known about the health implications of advanced glycation end products (AGEs) in Indian diets. 38 overweight or obese people participated in a 12-week clinical research in which they were given either a low-AGE or high-AGE diet.
The low-AGE group had lower postload plasma glucose levels and better insulin sensitivity, according to the results. According to the study, cooking techniques have a big impact on dietary AGE content and general health because traditional, minimally processed foods like fruits, vegetables, and whole grains have lower AGE levels.
